Cancer Research

Dr. Christopher Patil

Main Areas of Expertise Cancer biology; Neuroscience; Protein biochemistry; Signal transduction Secondary Areas of Expertise Developmental biology; Immunology; Microbiology; Biophysics Biography Dr Christopher Patil pursued a Ph.D. at the University of California-San Francisco, studying signal transduction in cellular stress responses. At UCSF, thesis work involved some of the earliest functional genomics studies to use expression profiling by microarrays. After a postdoctoral fellowship at the Lawrence Berkeley National Laboratory, he moved on to senior scientist positions at the Buck Institute for Research on Aging and most recently the Broad Institute of MIT and Harvard. Following his thesis work, his research career focused on the mechanisms of cellular senescence, the role of aging in cancer, and the transcriptional changes associated with neuronal aging. In collaboration with colleagues, he discovered that senescent cells secrete inflammatory factors that contribute to oncogenesis and age-related decline in tissue function, and revealed the molecular mechanisms that regulate this program of inflammatory gene expression. Qualifications PhD Biochemistry and Cell Biology; University of California BS Biological Sciences, Stanford University 2008-ongoing Editorial board member, PLoS ONE Current Activity Scientific editor since 2007 and has edited upwards of 1000 manuscripts. Has several writing projects ongoing.